Post-SSRI Sexual Dysfunction: Preclinical to Clinical. Is It Fact or Fiction? (2018)
Post-SSRI Sexual Dysfunction: Preclinical to Clinical. Is It Fact or Fiction? Enis Rauf Coskuner , MD, FECSM 1 , , , Mehmet Gokhan Culha , MD 2 , Burak Ozkan , MD 1 , Elcin Orhan Kaleagasi 3 1 Department of Urology, Acibadem Mehmet Ali Aydinlar University School of Medicine, Istanbul, Turkey 2 Department of Urology, Health Sciences University, Okmeydani Training and Research Hospital, Istanbul, Turkey 3 Department of Psychology, Acibadem Bakirkoy Hospital, Istanbul, Turkey Received 7 October 2017, Accepted 29 November 2017, Available online 17 February 2018 https://doi.org/10.1016/j.sxmr.2017.11.004 Abstract Introduction Selective serotonin reuptake inhibitors (SSRIs) are a widely used class of drug for various psychiatric disorders during the lifespan, including pregnancy, lactation, childhood, and adolescence. Deterioration in sexual functioning is a major and serious adverse effect of SSRIs. There is emerging evidence that SSRIs can have long-