Post-SSRI Sexual Dysfunction (PSSD): Biological Plausibility, Symptoms, Diagnosis, and Presumed Risk Factors (2021)
Sex Med Rev . 2021 Oct 6;S2050-0521(21)00060-3. doi: 10.1016/j.sxmr.2021.07.001 Post-SSRI Sexual Dysfunction (PSSD): Biological Plausibility, Symptoms, Diagnosis, and Presumed Risk Factors Liran C Peleg 1 , David Rabinovitch 2 , Yaakov Lavie 1 , Deya M Rabbie 3 , Itai Horowitz 2 , Eyal Fruchter 4 , Ilan Gruenwald 5 1 - Private Clinic, Haifa, Israel. 2 - Rambam Healthcare Campus, Psychiatry Department, Haifa, Israel. 3 - Ahram Canadian University, Neuropharmacology, 6th of October City, Egypt. 4 - Bruce Rappaport Medicine Faculty, Haifa, Israel. 5 - Rambam Healthcare Campus, Neuro-Urology Unit, Haifa, Israel. Electronic address: I_gruenwald@rmc.gov.il. PMID: 34627736 DOI: 10.1016/j.sxmr.2021.07.001 Abstract Introduction: Post-SSRI sexual-dysfunction (PSSD) is an iatrogenic syndrome, the underlying neurobiological mechanisms of which are unclear. Symptom onset follows cessation of serotonergic antidepressants i.e. Selective Serotonin and Norepinephrine Reuptake Inhibi