Disfunzioni sessuali post-SSRI

17 luglio 2017, Rxisk.org Diagnosi Una delle cose che RxISK può offrire a qualcuno con PSSD, Disfunzione sessuale Post Ro-Accutane, problemi di ritiro/sospensione persistenti, o una serie di altri problemi è il riconoscimento. Sì, questo farmaco può causare questo problema. Il semplice riconoscimento può essere utile. Nelle impostazioni legali un appoggio può cambiare la vita. Ma nella vita quotidiana, per qualcuno con problemi di ritiro in particolare, una diagnosi porta un'aspettativa di più - che si possa fare qualcosa per mettere le cose a posto. Nel momento in cui le persone vengono su RxISK con domande o vengono da me in una clinica nel Galles del Nord, molti di loro hanno provato tutte le opzioni ovvie - lenta dismissione, passaggio a soluzioni liquide, esercizio fisico ecc. - e hanno ancora problemi. Essi, e a volte le loro famiglie, hanno cominciato a stancarsi.   "Ora verrai a dirmi cosa fare per sistemare questa follia, vero?"   Stuart ...

Disfunción sexual persistente tras el tratamiento con inhibidores selectivos de la recaptación de serotonina: a propósito de un caso tras la retirada de paroxetina Post-serotonine selective reuptake inhibitors persistent sexual dysfunction after serotonine selective reuptake inhibitors treatment: A case report after stopping paroxetine Omar Walid Muquebil Ali Al Shaban Rodríguez a , Enrique Álvarez de Morales Gómez-Moreno b ,  Jennifer Fernández Fernández a ,  Carmen Fresno García c ,  María del Mar Fernández Fernández a a Centro de Salud Mental de Luarca, Luarca, Asturias, España b Centro de Salud Mental IV, Gijón, Asturias, España c Unidad Docente Multiprofesional de Salud Mental de Asturias, Oviedo, Asturias, España Recibido 09 mayo 2017, Aceptado 17 mayo 2017 Abstract Recent evidence suggests that the sexual dysfunction that often appears during treatment with s...

Depression pills sabotaged my love life: Woman reveals how anti-depressants crushed her libido Read more: http://www.dailymail.co.uk/health/article-4332998/Can-depression-pills-sabotage-love-life.html#ixzz4lzSjMiof https://www.pressreader.com/uk/daily-mail/20170321/282720521783005 (da tradurre)

Sex Med Rev. 2017 Jun 19. pii: S2050-0521(17)30046-X. doi: 10.1016/j.sxmr.2017.05.002. [Epub ahead of print] Sexual Consequences of Post- SSRI Syndrome. Reisman Y 1 . 1  Amstelland Hospital, Amstelveen, The Netherlands. Electronic address: uro.amsterdam@gmail.com. Abstract   INTRODUCTION: Sexual dysfunctions are well-known side effects of selective serotonin reuptake inhibitor ( SSRI ) use. Altered libido, erectile dysfunction, vaginal dryness, ejaculatory disorders, and orgasmic problems are frequently reported by patients treated with SSRIs. Moreover, these antidepressant-emergent sexual dysfunctions do not always resolve after discontinuation of the medication and can persist indefinitely. These complaints are termed post- SSRI sexual dysfunctions (PSSD). AIM: To examine the existence of this clinical entity, possible theoretical mechanisms, possible risk factors, and possible treatment modalities. METHODS: Through literature r...

Int J Risk Saf Med. 2016 Mar 16;28(1):1-12. doi: 10.3233/JRS-160668. Persistent sexual dysfunction after early exposure to SSRIs: Systematic review of animal studies. Simonsen AL , Danborg PB , Gøtzsche PC . Abstract   BACKGROUND: Sexual dysfunction is a common adverse effect of selective serotonin reuptake inhibitors (SSRIs) and there is a concern that the sexual harms might persist after discontinuation of therapy. OBJECTIVE: To assess whether the use of SSRIs in animals can lead to persistent sexual dysfunction. METHODS: Systematic review of animal studies measuring sexual behaviour after end of treatment with SSRIs or serotonin norepinephrine reuptake inhibitors . DATA SOURCES: We searched PubMed and EMBASE. RESULTS: We included 14 studies. The general quality of the studies was poor. Only four studies reported use of randomisation and none mentioned allocation concealment. All studies used placebo and were therefore blinded. For rats exp...

J Clin Psychopharmacol. 2015 Jun;35(3):273-8. doi: 10.1097/JCP.0000000000000300. Post-SSRI Sexual Dysfunction : Clinical Characterization and Preliminary Assessment of Contributory Factors and Dose-Response Relationship. Ben-Sheetrit J 1 , Aizenberg D , Csoka AB , Weizman A , Hermesh H . 1 From the *Geha Mental Health Center, Petah Tikva; †Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; and ‡Department of Anatomy, School of Medicine, Howard University, Washington D.C. Abstract   Emerging evidence suggests that sexual dysfunction emerging during treatment with selective serotonin reuptake inhibitors (SSRIs) and/or serotonin-norepinephrine reuptake inhibitors (SNRIs) persists in some patients beyond drug discontinuation ( post-SSRI sexual dysfunction [PSSD]). We sought to identify and characterize a series of such cases and explore possible explanatory factors and exposure-response relationship. Subjects who responded to an in...

Eur J Pharmacol. 2015 Apr 15;753:263-8. doi: 10.1016/j.ejphar.2014.11.031. Epub 2014 Dec 4. Penile anesthesia in Post SSRI Sexual Dysfunction (PSSD) responds to low-power laser irradiation: a case study and hypothesis about the role of transient receptor potential (TRP) ion channels. Waldinger MD 1 , van Coevorden RS 2 , Schweitzer DH 3 , Georgiadis J 4 . 1  Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of BetaSciences, Utrecht University, Universiteitslaan 99, 3584 CG Utrecht, The Netherlands; Private Practice Psychiatry and Neurosexology, Amstelveen, The Netherlands. Electronic address: md@waldinger.demon.nl. 2  Medisch Centrum Buitenveldert, Amsterdam, The Netherlands. 3  Department of Internal Medicine and Endocrinology, Reinier de Graaf Groep of Hospitals, Delft-Voorburg, The Netherlands. 4  Department of Neuroscience, Section Anatomy, University Medical Center Groningen, University of Groningen, ...

Int J Risk Saf Med. 2014;26(2):109-16. doi: 10.3233/JRS-140617. One hundred and twenty cases of enduring sexual dysfunction following treatment. Hogan C 1 , Le Noury J 1 , Healy D 1 , Mangin D 2 . 1  North Wales Department of Psychological Medicine, Bangor, Wales, UK. 2  David Braley & Nancy Gordon Chair of Family Medicine, Department of Famil   Abstract   BACKGROUND: There have been reports for over a decade linking serotonin reuptake inhibitors, finasteride and isotretinoin with enduring sexual dysfunction after treatment stops. OBJECTIVE: To explore the clinical pictures linked to all 3 drugs. METHODS: We have selected 120 reports to RxISK.org reporting the problem and mined these for data on age, gender, drug of use, and impact of the problem. RESULTS: The data make it clear that the three drugs show extensive overlap in symptom profile, regardless of sex or country of origin. CONCLUSIONS: The availability of 120 ...

Tijdschr Psychiatr. 2014;56(5):336-40. [Does sexual dysfunction persist upon discontinuation of selective serotonin reuptake inhibitors?] [Article in Dutch] Ekhart GC , van Puijenbroek EP . Abstract   BACKGROUND: Cases reported in the literature suggest that in some individuals sexual dysfunction associated with selective serotonin reuptake inhibitors (SSRIS) may persist following the discontinuation of ssris. AIM: To find out how many reports of persistent sexual dysfunction associated with the use of ssris were received by the Netherlands Pharmacovigilance Centre, Lareb. METHOD: The database of the Netherlands Pharmacovigilance Centre Lareb was searched for reports of sexual dysfunction in patients who had been using SSRIS and whose sexual functioning had not returned to normal at the time of notification. RESULTS: The database of the Netherlands Pharmacovigilance Centre Lareb contained 19 reports of persistent sexual dysfunction in pati...

THE IMPACT OF PERSISTENT SEXUAL SIDE EFFECTS OF SELECTIVE SEROTONIN REUPTAKE INHIBITORS AFTER DISCONTINUING TREATMENT: A QUALITATIVE INVESTIGATION   Rebecca Diane Stinson 2013 Theses and Dissertations - University of Iowa This dissertation is available at Iowa Research Online: http://ir.uiowa.edu/etd/5061 Abstract This dissertation details a qualitative study that examined nine individuals living with sexual side effects of SSRIs that had persisted after the discontinuation of pharmacological treatment (referred to as post-SSRI sexual dysfunction or PSSD). The investigation sought to answer the following research questions: (1) How do individuals with persistent sexual side effects make sense of and meaning from their experience?; (2) How have these individuals' sense of self or identity changed over the course of their sexual difficulties?; and (3) What role could a counseling psychologist have had in helping the individual with his or her situation? Using I...

Int J STD AIDS. 2009 Jan;20(1):68-9. doi: 10.1258/ijsa.2008.008402. Persistent sexual dysfunction in genitourinary medicine clinic attendees induced by selective serotonin reuptake inhibitors. Farnsworth KD , Dinsmore WW . PMID: 19103903 DOI: 10.1258/ijsa.2008.008402 [Indexed for MEDLINE]  LINK: http://www.ncbi.nlm.nih.gov/pubmed/19103903 http://www.mediafire.com/view/2ing236fwwzkx36/09_01_persistent+sexual+dysfunction_farnsworth.pdf TRADUZIONE ITALIANA: Disfunzioni sessuali urogenitali persistenti indotte dagli inibitori selettivi della ricaptazione della serotonina.

J Sex Marital Ther.  2008;34(2):150-9. doi: 10.1080/00926230701636205. Persistent genital arousal disorder in women: case reports of association with anti-depressant usage and withdrawal. Leiblum SR 1 ,  Goldmeier D . 1 Robert Wood Johnson Medical School, Department of Psychiatry, University of Medicine and Dentistry of New Jersey, Piscataway, New Jersey 08854, USA. leiblum@umdnj.edu Abstract Little is known with certitude about the triggers of persistent genital arousal disorder (PGAD) in women, although there appears to be certain common features of the disorder. Women complain of unbidden feelings of genital arousal that are qualitatively different from sexual arousal that is preceded by sexual desire/and or subjective arousal. The majority of women find PGAD distressing and report only brief relief with orgasm. In this article, we describe five women who believe they developed PGAD either after withdrawing from selective serotonin reuptake inhibitor ...

Persistence of Sexual Dysfunction Side Effects after Discontinuation of Antidepressant Medications: Emerging Evidence DOI: 10.2174/1874350100801010042 Audrey Bahrick · University of Iowa Abstract Post-market prevalence studies have found that Selective Serotonin Reuptake Inhibitor (SSRI) and Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) sexual side effects occur at dramatically higher rates than initially reported in pre-market trials. Prescribing and practice conventions rest on the untested assumption that individuals who develop sex-ual dysfunction secondary to SSRI and SNRI antidepressant medications return fully to their pre-medication sexual func-tioning baseline shortly after discontinuing treatment. Most individuals probably do return to their previous level of sexual functioning, however recent case reports, consumer-provided Internet-based information, incidental research findings, and empirical evidence of persistent post SSRI sexual benefits in the p...

J Sex Med. 2008 Jan;5(1):227-33. doi: 10.1111/j.1743-6109.2007.00630.x. Persistent sexual dysfunction after discontinuation of selective serotonin reuptake inhibitors. Csoka AB 1 , Bahrick A , Mehtonen OP . 1 University of Pittsburgh--Medicine, Pittsburgh, PA, USA. csokaA@dom.pitt.edu Abstract   INTRODUCTION: Sexual dysfunctions such as low libido, anorgasmia, genital anesthesia, and erectile dysfunction are very common in patients taking selective serotonin reuptake inhibitors (SSRIs). It has been assumed that these side effects always resolve after discontinuing treatment, but recently, four cases were presented in which sexual function did not return to baseline. Here, we describe three more cases. Case #1: A 29-year-old with apparently permanent erectile dysfunction after taking fluoxetine 20 mg once daily for a 4-month period in 1996. Case #2: A 44-year-old male with persistent loss of libido, genital anesthesia, ejaculatory anhedonia, and e...

Prolonged Post-Treatment Genital Anesthesia and Sexual Dysfunction Following Discontinuation of Citalopram and the Atypical Antidepressant Nefazodone Article  · The Open Women’ Health Journal, December 2007 DOI: 10.2174/187429120701011021 Robert P Kauffman Texas Tech University Health Sciences Center Amanda Murdock Abstract SSRI therapy is commonly associated with sexual side effects, but it is assumed that these distressing symp-toms resolve with termination of therapy. The atypical antidepressant nefazodone is infrequently associated with sexual dysfunction and may be substituted for SSRI's when sexual symptoms are intolerable. Recently, scattered case reports of persistent sexual dysfunction and genital anesthesia persisting well after termination of SSRI antidepressant therapy have surfaced. In each case, the underlying depressive disorder was in remission. Case: A 32-year old women with major depression was treated with citalopram but switched t...