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Estimating the risk of irreversible post-SSRI sexual dysfunction (PSSD) due to serotonergic antidepressants. (2023)

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Open Access Published:  21 April 2023 Estimating the risk of irreversible post-SSRI sexual dysfunction (PSSD) due to serotonergic antidepressants Joseph Ben-Sheetrit ,  Yehonathan Hermon ,  Shlomo Birkenfeld ,  Yehiel Gutman ,  Antonei B. Csoka  &  Paz Toren   Annals of General Psychiatry   volume  22 , Article number:  15  ( 2023 ) details Abstract Background Sexual dysfunction is a common side effect of Serotonergic antidepressants (SA) treatment, and persists in some patients despite drug discontinuation, a condition termed post-SSRI sexual dysfunction (PSSD). The risk for PSSD is unknown but is thought to be rare and difficult to assess. This study aims to estimate the risk of erectile dysfunction (ED) and PSSD in males treated with SAs. Methods A 19-year retrospective cohort analysis was conducted using a computerized database of the largest HMO in Israel. ED was defined by phosphodiesterase-5 inhibitors prescript...

Progetto di ricerca sulla PSSD dell'Università degli Studi di Roma Tor Vergata

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Da questo post su Reddit del 30 Marzo 2023. Tor Vergata University of Rome PSSD Research project Postato da u/PSSD_Uniroma2 Salve, Siamo un gruppo di ricerca internazionale condotto dalla Cattedra di Endocrinologia e Sessuologia Medica (ENDOSEX) dell’Università di Roma Tor Vergata. La nostra ricerca è rivolta a soggetti fluenti in lingua inglese e italiana, che hanno o hanno avuto problematiche di carattere sessuale associate all'uso di farmaci inibitori selettivi della ricaptazione della serotonina (selective serotonin reuptake inhibitors – SSRI) / inibitori della ricaptazione di serotonina-noradrenalina (serotonin-norepinephrine reuptake inhibitors – SNRI). La partecipazione al nostro studio prevede la compilazione di un questionario in forma anonima, il cui completamento richiede circa 60 minuti. Su richiesta del partecipante, alla fine del questionario verrà inoltre prodotto e successivamente inviato al suddetto un documento di report. Sottolineiamo che tale report non ha in a...

Post-SSRI sexual dysfunction and SSRI induced sexual dysfunction - literature review (2023)

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Post-SSRI sexual dysfunction and SSRI induced sexual dysfunction - literature review Journal of Education, Health and Sport 2023-04-11 | Journal article DOI: 10.12775/JEHS.2023.19.01.007 CONTRIBUTORS: Eliasz Panek; Damian Jasłowski; Mateusz Rzeszutko; Przemysław Raczkiewicz; Dominika Panasiuk; Mateusz Skrętowicz; Patrycja Szponarowicz; Bartosz Snopkowski; Tomasz Korzec; Jakub Sosnowski Abstract Introduction: Selective serotonin reuptake inhibitors (SSRIs) are one of the most commonly used drugs. One of the most common side effects are those related to sexual function. We can divide them into sexual dysfunction occurring during the use of SRRIs and those occurring and persisting after discontinuation of SSRIs. Purpose: To review available PubMed data on SSRI-related sexual dysfunction, epidemiology, symptoms and treatment. Current state of knowledge: SSRIs are first-line drugs for depression and other mental disorders. Their use can cause sexual dysfunction. SSRI-induced sexual disor...

Thesis: Understanding the Lived Experiences of People with Sexual Difficulties Resulting from Using and Discontinuing Antidepressants - Emily Rice, Ottawa, Canada, 2023

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Description Title: Understanding the Lived Experiences of People with Sexual Difficulties Resulting from Using and Discontinuing Antidepressants Authors: Rice, Emily Date: 2023-04-06 Abstract :  Many studies have demonstrated that antidepressants can cause a variety of side effects, including sexual difficulties. These sexual difficulties can persist after discontinuation of antidepressants – a condition known as post-SSRI sexual dysfunction (PSSD). Researchers have found that prescribers are not informing their patients of the sexual side effects of antidepressants and PSSD. The purpose of this study was to explore the lived experiences of those who have experienced sexual difficulties as a result of using and withdrawing from antidepressants. Ten (10) participants were recruited through a patient advocacy group, the Canadian PSSD Society, to participate in individual semi-structured interviews. The results were analyzed using descriptive phenomenological analysis. Eight themes an...